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Poor Sleep and Insulin Resistance

Poor Sleep and Insulin Resistance

Observational data has demonstrated an association with reduced sleep and reduced insulin sensitivity. When we look at clinical trials we can see the relationship between poor sleep quality and disruptions to glucose metabolism. There are a couple ways that sleep restriction can promote insulin resistance and one of these ways is because sleep restriction can lead to activation of the HPA axis which could lead to elevated cortisol levels, and elevated cortisol levels can contribute towards insulin resistance. Another potential way for poor sleep to promote insulin resistance is by disrupting our appetite regulating hormones leptin and ghrelin, which could lead to increased appetite, weight gain and then future insulin resistance. We also see an elevation of inflammatory markers in response to sleep restrictions, like IL-1, IL-6, IL-17, TNF- and hsCRP, and these markers have been linked to insulin resistance. The good news is that if you are sleep deprived and have issues with insulin resistance you can improve some of these markers by improving your sleep quality. ------------------------------- This video is for information and educational purposes only. The information presented is the opinion of Daniel Quinones and is not intended to replace medical advise provided by your General Practitioner or primary health care provider. Please consult you Doctor or GP prior to embarking on any nutritional protocol.
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